Human Glial Fibrillary Acidic Protein (GFAP) Matched Antibody Pair & Calibrator

Capture mAb: RDM016 | Detection mAb: RDM017 | Calibrator: RDP006

Engineered for ultrasensitive sandwich immunoassay development. Specifically quantifies reactive astrogliosis and blood-brain barrier disruption with zero cross-reactivity toward other intermediate filaments (vimentin, desmin), validated for blood-based TBI and neurodegenerative diagnostic platforms.

Validated Platforms: CLIA (Magnetic Microparticle), ELISA, Lateral Flow, Simoa
Specificity: Specific to human GFAP (No cross-reactivity with vimentin or peripherin)
Purity: >95% determined by SDS-PAGE analysis
Host / Clonality: Mouse Monoclonal Antibody (In-House Production)
Supply Capability: Multi-gram industrial batch capacity with lot-to-lot consistency

Request Evaluation Sample → Download CoA / Tech Dossier

Standard Matched Formulation & Ordering Information

Recommended matched antibody pairs and authentic calibrators for clinical sandwich assay development:

Component Type	Catalog No.	Target / Specificity	Host / Source	Formulation / Buffer
Capture Monoclonal Antibody	RDM016	Human GFAP (Specific Epitope)	Mouse mAb	PBS (pH 7.4), Preservative-free
Detection Monoclonal Antibody	RDM017	Human GFAP (Conjugation-ready)	Mouse mAb	PBS (pH 7.4), Preservative-free
Recombinant Calibrator Protein	RDP006	Full-length Human GFAP	E. coli Expression	Lyophilized powder

Analytical Performance & Assay Development Highlights

Intermediate Filament Specificity

Eliminates cross-binding with structurally homologous intermediate filaments like desmin and vimentin in complex human serum and plasma matrices.

Sub-Picogram Blood Sensitivity

Optimized for magnetic particle CLIA platforms to detect minute blood-brain barrier leakage in mild TBI and early-stage astrogliosis.

Acute & Chronic Trauma Correlation

Validated across clinical protocols assessing acute concussion severity, intracranial injury risk, and progressive neurodegenerative decline.

Request Validation Samples or Inquire for Bulk Industrial Supply

Sample evaluation packs (50 µg – 1 mg) are available for verified IVD assay developers. Batch-specific Certificates of Analysis (CoA) are included with each shipment.

Get in Touch with Our Scientists →